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. 2014 Dec 26;9(12):e115684. doi: 10.1371/journal.pone.0115684

Figure 2. Knockdown of JARID2 antagonized TGF-ß-induced morphological changes of A549 cells.

Figure 2

(A) Cell morphological changes of A549 cells after TGF-ß treatment. A549 cells were infected with retroviruses expressing control shRNA or JARID2 shRNA (described as JARID2 KD) without or with the treatment of 1 ng/ml of TGF-ß for 48 hours. (B) Immunofluorescence images of cells showing the localization of E-cadherin. The panels of A549 cells with the same arrangement with (A) were stained with anti-E-cadherin antibody and with DAPI. (C) Fluorescence images of cells showing reorganization of actin cytoskeleton by staining with TRITC-phalloidin (Actin) and with DAPI. Scale bars: 20 µm.