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. 2014 Dec 26;9(12):e115609. doi: 10.1371/journal.pone.0115609

Table 2. Changes in CK2 gene expression in breast cancer.

Gene P-Value Fold Change Rank (Top %) Dataset #Samples Reference
Ductal Breast Carcinoma
CK2α 7.43 10−11 2 1% Richardson 2 47 [65]
CK2α' 2.05 10−4 −1.6 3% Sorlie 85 [66]
9.15 10−4 −1.6 6% Sorlie Breast 2 167 [67]
1.79 10−4 −1.5 10% Richardson 2 47 [65]
Invasive Ductal Breast Carcinoma
CK2α 8.09 10−28 1.6 4% TCGA Breast 593 [68]
2.06 10−70 1.5 4% Curtis 2136 [69]
CK2α' 4.04 10−20 −1.5 10% TCGA Breast 593 [68]
5.39 10−50 −1.5 5% Curtis 2136 [69]
1.08 10−4 −1.6 4% Zhao 64 [70]
CK2β 2.48 10−51 1.4 8% Curtis 2136 [69]
Lobular Breast Carcinoma
CK2α' 6.37 10−4 −1.5 4% Zhao 64 [70]
Invasive Lobular Breast Carcinoma
CK2α' 3.75 10−11 −1.6 5% TCGA Breast 593 [68]
4.51 10−43 −1.6 3% Curtis 2136 [69]
CK2β 8.00 10−39 1.4 2% Curtis 2136 [69]
Mucinous Breast Carcinoma
CK2α 4.33 10−5 1.5 2% TCGA Breast 593 [68]
1.39 10−16 1.4 3% Curtis 2136 [69]
Invasive Mucinous Breast Carcinoma
CK2β 2.48 10−51 1.4 8% Curtis 2136 [69]
Breast Carcinoma
CK2α' 3.09 10−5 −1.7 8% Curtis 2136 [69]
Invasive Breast Carcinoma
CK2α 3.58 10−15 1.5 6% TCGA Breast 593 [68]
Invasive Breast Carcinoma Stroma
CK2α 1.2 10−28 −2.2 2% Finak Breast 59 [71]
CK2α' 7.45 10−12 −6.8 15% Finak Breast 59 [71]
CK2β 3.02 10−20 −5.7 7% Finak Breast 59 [71]
Tubular Breast Carcinoma
CK2α' 3.22 10−36 −1.8 2% Curtis 2136 [69]
Invasive Medullary Carcinoma
CK2αP 1.2 10−9 1.5 5% Curtis 2136 [69]
CK2β 1.4 10−10 1.6 4% Curtis 2136 [69]

Different subtypes of breast cancer are analyzed and p-values, fold changes, and datasets are included.