Table 2. Changes in CK2 gene expression in breast cancer.
Gene | P-Value | Fold Change | Rank (Top %) | Dataset | #Samples | Reference |
Ductal Breast Carcinoma | ||||||
CK2α | 7.43 10−11 | 2 | 1% | Richardson 2 | 47 | [65] |
CK2α' | 2.05 10−4 | −1.6 | 3% | Sorlie | 85 | [66] |
9.15 10−4 | −1.6 | 6% | Sorlie Breast 2 | 167 | [67] | |
1.79 10−4 | −1.5 | 10% | Richardson 2 | 47 | [65] | |
Invasive Ductal Breast Carcinoma | ||||||
CK2α | 8.09 10−28 | 1.6 | 4% | TCGA Breast | 593 | [68] |
2.06 10−70 | 1.5 | 4% | Curtis | 2136 | [69] | |
CK2α' | 4.04 10−20 | −1.5 | 10% | TCGA Breast | 593 | [68] |
5.39 10−50 | −1.5 | 5% | Curtis | 2136 | [69] | |
1.08 10−4 | −1.6 | 4% | Zhao | 64 | [70] | |
CK2β | 2.48 10−51 | 1.4 | 8% | Curtis | 2136 | [69] |
Lobular Breast Carcinoma | ||||||
CK2α' | 6.37 10−4 | −1.5 | 4% | Zhao | 64 | [70] |
Invasive Lobular Breast Carcinoma | ||||||
CK2α' | 3.75 10−11 | −1.6 | 5% | TCGA Breast | 593 | [68] |
4.51 10−43 | −1.6 | 3% | Curtis | 2136 | [69] | |
CK2β | 8.00 10−39 | 1.4 | 2% | Curtis | 2136 | [69] |
Mucinous Breast Carcinoma | ||||||
CK2α | 4.33 10−5 | 1.5 | 2% | TCGA Breast | 593 | [68] |
1.39 10−16 | 1.4 | 3% | Curtis | 2136 | [69] | |
Invasive Mucinous Breast Carcinoma | ||||||
CK2β | 2.48 10−51 | 1.4 | 8% | Curtis | 2136 | [69] |
Breast Carcinoma | ||||||
CK2α' | 3.09 10−5 | −1.7 | 8% | Curtis | 2136 | [69] |
Invasive Breast Carcinoma | ||||||
CK2α | 3.58 10−15 | 1.5 | 6% | TCGA Breast | 593 | [68] |
Invasive Breast Carcinoma Stroma | ||||||
CK2α | 1.2 10−28 | −2.2 | 2% | Finak Breast | 59 | [71] |
CK2α' | 7.45 10−12 | −6.8 | 15% | Finak Breast | 59 | [71] |
CK2β | 3.02 10−20 | −5.7 | 7% | Finak Breast | 59 | [71] |
Tubular Breast Carcinoma | ||||||
CK2α' | 3.22 10−36 | −1.8 | 2% | Curtis | 2136 | [69] |
Invasive Medullary Carcinoma | ||||||
CK2αP | 1.2 10−9 | 1.5 | 5% | Curtis | 2136 | [69] |
CK2β | 1.4 10−10 | 1.6 | 4% | Curtis | 2136 | [69] |
Different subtypes of breast cancer are analyzed and p-values, fold changes, and datasets are included.