Table 1. Genetic variants in the PROCR gene found in 3,771 Ghanaian children.

	SNP ID	Position Chr19 (build37)	Major/Minor Allele	Region	Relative positiona	AA exchange	Novel	MAF cases (N = 1,905)	MAF controls (N = 1,866)
1	ss1457457875	33758811	G/A	5′-UTR	c.-1147		YES	-	Singleton
2	rs113601425	33758824	C/T		c.-1134			0.007	0.007
3	ss1457457916	33758834	A/G		c.-1124		YES	0.001	0.001
4	ss1457457937	33758983	C/G		c.-975		YES	0.001	0.002
5	rs112681065	33759055	C/G		c.-903			0.006	0.008
6	ss1457457959	33759070	TA/-		c.-888		YES	Singleton	-
7	ss1457457984	33759072	CACA/-		c.-886		YES	Singleton	-
8	ss1457458010	33759093	C/A		c.-865		YES	0.002	0.001
9	rs115088244	33759104	G/T		c.-854			0.077	0.084
10	rs146473859	33759128	C/G		c.-830			0.001	0.001
11	ss1457458032	33759145	T/C		c.-813		YES	-	Singleton
12	rs2069940	33759272	C/G		c.-686			0.018	0.018
13	rs2069941	33759386	C/T		c.-572			0.013	0.012
14	ss1457458053	33759599	A/G		c.-359		YES	Singleton	-
15	rs113347910	33759639	C/A		c.-319			0.038	0.028
16	rs372603647	33759656	C/-		c.-301			-	Singleton
17	rs139617753	33759867	C/G	Ex1-UTR	c.-91			-	Singleton
18	ss1457458073	33759903	C/T		c.-55		YES	0.001	0.001
19	ss1457458095	33759972	G/A	Ex1	c.15	L5L	YES	0.001	0.001
20	rs145917629	33759978	G/A		c.21	P7P		0.004	0.003
21	ss1457458118	33760025	A/G		c.68	D23G	YES	Singleton	-
22	rs2069948	33762489	T/C	In1	c.71-16			0.125	0.126
23	rs141487483	33762664	A/G	Ex2	c.230	E77G		0.002	0.003
24	rs2069952	33763951	T/C	In2	c.323-20			0.132	0.14
25	COSM1222127	33764042	G/A	Ex3	c.395	E132K		-	Singleton
26	rs144485700	33764082	C/T		c.434	P145L		0.003	0.001
27	rs201040729	33764137	C/T		c.489	F163F		Singleton	-
28	rs116737636	33764292	C/T	In3	c.601+43			Singleton	-
29	rs148966205	33764458	T/A		c.602-43			0.001	-
30	rs145801152	33764542	G/A	Ex4	c.643	V215I		0.001	-
31	rs867186	33764554	A/G		c.655	S219G		0.057	0.059
32	rs9574	33764632	G/C	3'-UTR	c.*16			0.132	0.139
33	rs141265473	33764667	G/C		c.*51			0.006	0.004
34	ss1457458141	33764697	C/G		c.*81		YES	Singleton	-
35	ss1457458164	33764702	A/G		c.*86		YES	-	Singleton
36	ss1457458186	33764703	C/A		c.*87		YES	-	Singleton
37	rs146262354	33764758	C/G		c.*142			0.006	0.004
38	rs115542162	33764978	C/T		c.*362			0.032	0.030
39	ss1457458207	33765308	A/G		c.*692		YES	-	0.002
40	ss1457458230	33765332	A/G		c.*710		YES	-	Singleton
41	ss1457458251	33765355	A/G		c.*739		YES	0.001	0.001

AA, amino acid; Ex, exon; In, intron; MAF, minor allele frequency.

^aReference sequence NCBI NM_006404.4.