Table 1. Up- and down regulation of CAR-regulated genes in the livers of WT and KO treated with PB.
| Fold change | ||||
| Reported | Gene symbol | Gene name | KO | WT |
| Up-regulated | Ces2a | carboxylesterase 2 a | 2.493 | 2.038 |
| Cyp2b13 | cytochrome P450 family 2, subfamily b, polypeptide 13 | 4.695 | 22.644 | |
| Cyp2b10 | cytochrome P450 family 2, subfamily b, polypeptide 10 | 5.536 | 28.008 | |
| Cyp2c39 | cytochrome P450 family 2, subfamily c, polypeptide 39 | 10.059 | 2.542 | |
| Cyp2c55 | cytochrome P450 family 2, subfamily c, polypeptide 55 | 6.237 | 4.995 | |
| Cyp3a44 | cytochrome P450 family 3, subfamily a, polypeptide 44 | 7.582 | ||
| Dio1 | deiodinase, iodothyronine, type I | 3.210 | 2.387 | |
| Gadd45b | growth arrest and DNA-damage-inducible 45 beta | 3.844 | ||
| Gsta2 | glutathione S-transferase, alpha 2 | 2.604 | ||
| Insig1 | insulin induced gene 1 | 2.946 | ||
| Insig2 | insulin induced gene 2 | 2.194 | ||
| Down-regulated | Cyp7a1 | cytochrome P450, family 7, subfamily a, polypeptide 1 | 3.289 | |
Blank means no significant alteration by PB. Cut-off: 2.0, p<0.05 (ANOVA).