Table 3.
ΔV per | CVm ancestor5 (% per | CVm MA6 (% per | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Variance1 (95% CIs) | F-ratio test2 | ΔV3 | generation4 = Vm | generation) | generation) | |||||||||
Strain | First Anc | First MA | Second Anc | Second MA | First | Second | First | Second | First | Second | First | Second | First | Second |
CC-1952 | 0 (0,0) | 6.93×10−4 (3.56×10−4, 1.89×10−3) | 6.99×10−5 (3.19×10−5, 2.57×10−4) | 5.99×10−4 (3.15×10−4, 1.55×10−3) | NA* | 8.57* | 6.93×10−4 | 5.29×10−4 | 6.79×10−7 | 5.18×10−7 | 0.54 | 0.55 | 0.82 | 0.66 |
CC-2342 | 2.86×10−17 (1.30×10−17, 1.05×10−16) | 1.47×10−3 (6.42×10−4, 6.08×10−3) | 2.43×10−4 (1.11×10−4, 8.90×10−4) | 9.82×10−4 (5.16×10−4, 2.55×10−3) | 5.14×1013* | 4.04* | 1.47×10−3 | 7.39×10−4 | 1.42×10−6 | 7.16×10−7 | 0.78 | 0.65 | 1.06 | 0.85 |
CC-2344 | 0 (0,0) | 6.3×10−4 (3.31×10−4, 1.64×10−3) | 0 (0,0) | 1.09×10−4 (5.75×10−5, 2.84×10−4) | NA* | NA* | 6.30×10−4 | 1.09×10−4 | 6.72×10−7 | 1.16×10−7 | 0.77 | 0.30 | 0.89 | 0.32 |
CC-2931 | 5.24×10−17 (2.39×10−17, 1.93×10−16) | 1.061×10−4 (5.46×10−5, 2.89×10−4) | 1.99×10−4 (9.07×10−5, 7.30×10−4) | 7.76×10−4 (4.16×10−4, 1.93×10−3) | 2.02×1012* | 3.9* | 1.06×10−4 | 5.77×10−4 | 1.03×10−7 | 5.63×10−7 | 0.19 | 0.58 | 0.25 | 0.71 |
CC-2937 | − | − | 7.15×10−21 (3.26×10−21, 2.62×10−20) | 2.91×10−4 (1.56×10−4, 7.24×10−4) | − | 4.07×1016* | − | 2.91×10−4 | − | 3.13×10−7 | − | 0.51 | − | 0.54 |
Columns show estimates from the first and second replicate assays. Anc = ancestor; MA = mutation accumulation lines.
1Among MA line variance component.
2Ancestral among-pseudoline variance component divided by the between line MA variance component; the critical value = 3.006 with df = 15,9 (*significant difference at the 5% level between MA and ancestral variance).
3Change in the among-line variance component of fitness between the MA lines and their ancestors.
4Mutational heritability calculated as ΔV /number of generations.
5Coefficients of mutational variance calculated as the square root of ΔV per generation divided by the mean fitness of the ancestral lines.
6Coefficients of mutational variance calculated as the square root of ΔV per generation divided by the mean fitness of the MA lines.