Figure 1. Heat intervention promoted proliferation, invasion and migration of HCC cells in vitro.

(A) HCCLM3 and HepG2 cells were cultured with or without heat intervention. The 24 h, 48 h and 72 h cell viability of HCC cells were measured using CCK8 assay. Heat intervention significantly promoted HCCLM3 and HepG2 cells proliferation. (B) The transwell assay demonstrated that the heat-treated HCCLM3 and HepG2 cells showed enhanced migration and invasion ability compared with the controls.