Table 1. Expected and identified frequency of patients with IDO1 Variant Alleles.

IDO1 Variant	Predicted Minor Allele Frequencies	Non-IBD Cohort (354 patients)	Crohn's Disease Cohort (734 patients)	P Value
rs4463407 (G to A)	N/A	0/181 (0%)	0/705 (0%)	-
rs12545877 (A to G)	N/A	0/180 (0%)	0/702 (0%)	-
rs35059413 (C to T)	0.7%–4.4%	5/345 (1.45%)	3/716 (0.42%)	0.122
rs35099072 (C to T)	1.4%–4.2%	0/351 (0%)	1/723 (0.14%)	1.000
7CA (Exon 7, C to A)*	0%–1.042%	0/337 (0%)	4/610 (0.66%)	0.303
9BPD (Exon 7, 9 base pair deletion)	0%–1.042%	1/346 (0.29%)**	0/722 (0%)	0.330

Notes: The denominator is shown to indicate the number of successful complete reads per genotype.

*All 7CA variants were homozygous while all other variants were single allele.

**This individual also carried a single allele of the rs25059413 variant.