Table 2. Expected and identified frequency of patients with IDO2 Variant Alleles.
Recessive Logistic Model | Number (and %) of homozygous minor allele | |||||
IDO2 Variant | Predicted Minor allele frequency | Estimate coefficient | P-value | Race | Non-IBD (177) | CD (686) |
rs4503083 (T to A) | 10.9%–50.0% | −1.295 | 0.025 | White | 66/142 (46.5%) | 399/614 (35.0%) |
Y359stop | Black | 6/34 (17.6%) | 13/63 (20.6%) | |||
Other | 0/1 (0%) | 7/9 (77.8%) | ||||
rs4736794 (A to G) | 6.7%–50.0% | −0.498 | 0.698 | White | 29/142 (46.5%) | 399/614 (35.0%) |
Black | 2/34 (5.9%) | 13/63 (3.2%) | ||||
Other | 0/1 (0%) | 6/9 (66.7%) | ||||
rs10109853 (C to T) | 18.2%–100% | −0.072 | 0.786 | White | 97/142 (68.3%) | 473/614 (77.0%) |
Black | 20/34 (58.8%) | 35/63 (55.6%) | ||||
Other | 1/1 (100%) | 7/9 (77.8%) | ||||
rs35212142(T to A) | 5.6%–50.0% | 12.923 | 0.981 | White | 8/142 (5.6%) | 28/614 (4.6%) |
Black | 2/34 (5.9%) | 0/63 (0%) | ||||
Other | 0/1 (0%) | 0/9 (0%) |