Table 4. Specific Phenotypic Data of Individual Patients with at Least 1 IDO1 Variant Allele.
Variant | Genotype | Sex | Race | Age at Dx | Family History | Surgery (N) | Montreal Location | Perianal Disease | Montreal Behavior | Extraintestinal Manifestations | Use of IMM/TNFα |
rs35059413 | AG | M | Black | 30 | Yes | Yes (2) | L3 | Yes | B3 | Yes | Yes |
rs35059413 | AG | F | Black | 17 | No | Yes (6) | L3 | Yes | B3 | Yes | Yes |
rs35059413 | AG | M | Black | 22 | No | Yes (1) | L2 | Yes | B1 | Yes | Yes |
rs35099072 | CA | F | Black | 43 | No | Yes (1) | L1 | No | B1 | Yes | Yes |
Exon 7, C to A | AA | F | White | 41 | Yes | Yes (3) | L1# | No | B2 | No | Yes |
Exon 7, C to A | AA | M | Black | 50 | No | Yes (1) | L3 | Yes | B2 | Yes | Yes |
Exon 7, C to A | AA | F | White | 18 | No | Yes (2) | L3 | Yes | B1 | No | Yes |
Exon 7, C to A | AA | M | White | 23 | No | Yes (1) | L3 | Yes | B2 | Yes | Yes |
Denotes upper small bowel involvement in addition to other location.
Abbreviations: IMM, immunomodulators; TNFα, Antibodies against Tumor Necrosis Factor alpha.