Figure 3. Incremental model performance for predicting prognosis assessed by starting with the clinical variables (Model I: age, NYHA class, and number of non-cardiac organs involved), followed by the conventional echocardiographic parameters (Model II: adding MAPSE and E/E′ to model I), and finally by adding advanced global LSR_dias (Model III).

MAPSE: mitral annular plane systolic excursion; E/E′: early diastolic peak filling velocity to tissue Doppler early diastolic septal mitral annular velocity ratio. LSR_dias: longitudinal peak early diastolic strain rate.