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. 2014 Dec 26;9(12):e116054. doi: 10.1371/journal.pone.0116054

Table 1. Detection of PIK3CA mutation (E542K, E545K, H1047R) by DNA sequencing and digital PCR analysis (only among the patients whose mutations were detected).

Patient ID Mutation
Direct sequencing Digital PCR analysis (mutant percentage)
31 H1047R, E542K H1047R (58.2%), E542K (41.0%)
10 H1047R H1047R (28.9%)
40 H1047R H1047R (25.8%), E542K (0.3%), E545K (0.2%)
18 H1047R H1047R (19.2%)
37 H1047R H1047R (16.7%), E542K (0.1%)
15 H1047R H1047R (6.8%)
41 H1047R E542K (0.2%)
27 E542K E542K (24.6%)
8 E545K E545K (20.9%)
23 Wild-type H1047R (7.7%)
34 Wild-type H1047R (5.1%), E545K (0.9%)
3 Wild-type H1047R (1.5%)
16 Wild-type H1047R (0.8%)
36 Wild-type H1047R (0.7%)
1 Wild-type H1047R (0.6%)
7 Wild-type H1047R (0.6%)
12 Wild-type H1047R (0.5%), E545K (0.3%)
26 Wild-type H1047R (0.4%), E542K (0.1%)
13 Wild-type E542K (0.4%)
39 Wild-type E545K (0.3%)
28 Wild-type E542K (0.1%), E545K (0.1%)
Frequencya 21% 49%
a

Frequency of the patient with mutated DNA.