. 2014 Dec 10;20(1):490–502. doi: 10.2119/molmed.2014.00048

Table 1.

NASH activity scoring in control and ethanol-treated OLETF and OLET rats.

	OLETF rats					OLET rats

Parameters	Control, 33 wks	Ethanol, 5 d/wk	Ethanol, 3 d/wk	Ethanol, 2 d/wk	Ethanol, 1 d/wk	Control, 33 wks	Ethanol, 5 d/wk	Ethanol, 1 d/wk
Steatosis	1.1 ± 0.2	2.1 ± 0.3^a	1.9 ± 0.3^a	2.0 ± 0.4^a	1.9 ± 0.3	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
Lobular inflammation	0.0 ± 0.0	1.4 ± 0.2^a	1.3 ± 0.2^a	1.1 ± 0.2^a	0.8 ± 0.1^a	0.0 ± 0.0	0.5 ± 0.1	0.0 ± 0.0
Hepatocyte ballooning	0.2 ± 0.0	2.6 ± 0.4^a	2.7 ± 0.4^a	2.5 ± 0.3^a	2.4 ± 0.3^a	0.0 ± 0.0	0.0 ± 0.0	0.0 ± 0.0
NAS (0–9)	1.3 ± 0.2	6.1 ± 0.9^a	5.9 ± 0.9^a	5.6 ± 0.9^a	5.1 ± 0.7^a	0.0 ± 0.0	0.5 ± 0.1	0.0 ± 0.0

Data are means ± SD of eight rats per group. Scores for steatosis (score 0–3), lobular inflammation (score 0–3) and hepatocyte ballooning (score 0–3) were summed to produce the NAS, thus ranging from 0 to 9.

P < 0.001 versus OLETF untreated control rats.