FIG 4.

Differentially abundant bacterial phylotypes identified by linear discriminant analysis (LDA) coupled with effect size measurements (LEfSe). Bacterial taxa enriched in healthy sites are indicated with positive linear discriminant analysis scores, and taxa enriched in periodontitis sites are indicated with negative linear discriminant analysis scores. Only taxa that met the significant linear discriminant analysis threshold of 3.5 are shown. Phylotypes that were also significantly different between the two groups by multivariate analysis are indicated by an asterisk. The oral taxon numbers are derived from the Human Oral Microbiome Database.