TABLE 2.
Micropollutant | Experimentally observed biotransformationa | No. of different bacterial taxa predicted to perform biotransformationb |
---|---|---|
Atenolol | Amide hydrolysis | 4,516 |
Azoxystrobin | Carboxylic acid ester hydrolysis | 3,894 |
Diazinon | Aromatic thiophosphate hydrolysis | 2,56 |
Ethofumesate | Ether dealkylation | 131 |
Isoproturon | Urea dealkylation and urea didealkylation | 0 |
Propachlor | Glutathione coupling, dehalogenation, and halosubstitution | 939 |
Ranitidine | S-oxidation and N-oxidation | 8 |
Trinexepac ethyl | Carboxylic acid ester hydrolysis | 3,894 |
Valsartan | Amide dealkylation | 0 |
Venlafaxine | Amine dealkylation and ether dealkylation | 68 |
The experimentally observed biotransformation types and biotransformation products were reported previously by Helbling et al. (24).
The NCBI protein search tool was used to search eight publically available sequence databases and retrieve all taxonomically assigned protein sequences for each UM-BBD-predicted enzyme.