Figure 2.
Multiplex cytokine production at baseline in a representative example of A) a clearer (duration of infection 25 weeks) and B) a persister (duration of infection 28 weeks) after stimulation with the three HCV peptide pools (Core-p7, NS2-3, NS4-5), control CEF peptides or PHA. Strong Type 1 cytokine responses (IFN-γ/IL-2) to HCV antigens are present in the clearer and absent in the persister. The dotted black line at 10 pg/mL represents the background cytokine production (media alone) in the assay.