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. 2015 Winter;14(1):77–87.

Table 1.

Preliminary screening of anticonvulsant activity in mice (i.p.).

Compounds R 1 R 2 MES(mg/Kg) a , b
200 100 30
5a n-C6H13 n-C2H5 0/3 0/3 0/3
5b n-C6H13 n-C3H7 0/3 0/3 0/3
5c n-C6H13 n-C4H9 0/3 0/3 0/3
5d n-C6H13 n-C5H11 0/3 0/3 0/3
5e n-C6H13 n-C6H13 2/3 1/3 0/3
5f n-C6H13 n-C7H15 - 3/3 2/3
5g n-C6H13 n-C8H17 3/3 2/3 0/3
5h n-C6H13 n-C10H21 1/3 0/3 0/3
5i n-C6H13 n-C12H25 0/3 0/3 0/3
5j n-C6H13 n-CH2C6H5 2/3 1/3 0/3
5k n-C7H15 n-C2H5 0/3 0/3 0/3
5l n-C7H15 n-C3H7 0/3 0/3 0/3
5m n-C7H15 n-C4H9 1/3 0/3 0/3
5n n-C7H15 n-C5H11 1/3 0/3 0/3
5o n-C7H15 n-C6H13 2/3 1/3 0/3
5p n-C7H15 n-C7H15 3/3 2/3 1/3
5q n-C7H15 n-C8H17 1/3 0/3 0/3
5r n-C7H15 n-C10H21 0/3 0/3 0/3
5s n-C7H15 n-C12H25 0/3 0/3 0/3
5t n-C7H15 n-CH2C6H5 2/3 1/3 0/3
a

Maximal electroshock: doses of 30, 100 and 200 mg/Kg were administrated intraperitoneally in mice. The animals were examined 0.5 h after administration.

b

n1/n2: the animals protected / the animals tested.