Skip to main content
. 2015 Winter;14(1):77–87.

Table 3.

Effects of compound 5f on chemical-induced seizures in mice (i.p.).

Chemical substances Compound Doses (mg/Kg) Test time (h) Clonic seizures (%) Tonic seizures
(%)
Lethality
(%)
Pentylenetetrazol DMSO - 0.5 100 100 100
Carbamazepine 50 0.5 100 0 10
5f 50 0.5 100 40 50
3-Mercaptopropionic DMSO - 0.5 100 100 100
acid Carbamazepine 50 0.5 100 20 10
5f 50 0.5 100 20 0
Bicuculline DMSO - 0.5 100 100 100
Carbamazepine 50 0.5 100 0 60
5f 50 0.5 100 0 20