Table 2.

Hazard ratios (95% CI) of the effect of tranexamic acid on all-cause mortality, bleeding and non-bleeding deaths by day since injury and time from injury to treatment

Days since injury	Time to treatment ≤3 h			Time to treatment >3 h
	All-cause	Bleeding	Non- bleeding	All-cause	Bleeding	Non- bleeding
0	0.78 (0.68, 0.90)	0.72 (0.60, 0.86)	0.89 (0.71, 1.11)	1.02 (0.76, 1.36)	1.28 (0.85, 1.93)	0.79 (0.51, 1.22)
1	0.86 (0.72, 1.02)	0.72 (0.55, 0.94)	0.98 (0.78, 1.23)	1.02 (0.80, 1.31)	1.47 (0.97, 2.21)	0.81 (0.59, 1.13)
2	0.86 (0.65, 1.13)	1.01 (0.58, 1.77)	0.82 (0.59, 1.12)	1.16 (0.81, 1.66)	1.61 (0.70, 3.70)	1.08 (0.72, 1.60)
3	0.95 (0.66, 1.37)	0.26 (0.09, 0.78)	1.20 (0.80, 1.81)	1.11 (0.73, 1.71)	2.76 (0.73, 10.39)	0.98 (0.62, 1.55)
4	0.94 (0.61, 1.45)	0.64 (0.18, 2.28)	0.99 (0.63, 1.57)	1.04 (0.62, 1.75)	1.04 (0.21, 5.13)	1.04 (0.60, 1.80)