Table 1.

Univariate and multivariate Cox regression analyses of prognostic factors in gastric cancer patients

	Univariate		Multivariate
Variable	RR (95% CI)	p value	RR (95% CI)	p value
Age	1.00 (0.98–1.02)	0.75	1.01 (0.99–1.02)	0.53
Gender
Male	0.99 (0.63–1.55)	0.97	0.91 (0.57–1.44)	0.68
Female	1.00		1.00
H. pylori
Positive	1.05 (0.56–1.97)	0.88
Negative	1.00
Lauren
Intestinal	0.67 (0.38–1.18)	0.17
Diffuse/mixed	1.00
Differentiation
Poor	1.24 (0.72–2.13)	0.44
Moderate/well	1.00
TNM stage
I	0.09 (0.03–0.28)	< 0.01	0.10 (0.03–0.31)	< 0.01
II	0.15 (0.07–0.32)	< 0.01	0.16 (0.07–0.34)	< 0.01
III	0.26 (0.15–0.45)	< 0.01	0.29 (0.16–0.50)	< 0.01
IV	1.00		1
OSR1 methylation
Methylated	2.32 (1.45–3.70)	< 0.01	1.70 (1.04–2.80)	0.04
Unmethylated	1.00		1.00

RR = relative risk; CI = confidence interval.