Table 2.

Table 2a. IgG1 Antibody levels across age groups in an area of stable malaria transmission
Antigen	Median level (AU) (min, max) for age groups:				P value ^a (trend for age)
Antigen	2–5 yr (n=14)	6–15 yr (n=30)	16–40 yr (n=44)	>40 yr (n=28)	P value ^a (trend for age)
CSP	2.54 (0.40,9.37)	3.21 (0.33,12.00)	1.85 (0.00,11.19)	2.74 (0.06,18.42)	0.259
LSA-1	2.35 (0.16,16.05)	2.19 (0.49,21.89)	2.08 (0.49,41.30)	2.38 (0.07,11.12)	0.835
TRAP	1.32 (0.02,7.44)	1.56 (0.31,6.28)	1.98 (0.56,5.32)	2.01 (0.31,9.20)	0.010
AMA-1	1.05 (0.08,4.78)	2.31 (0.30,4.21)	1.30 (0.00,4.87)	1.36 (0.31,5.19)	0.135
EBA-175	2.27 (0.02,11.83)	9.58 (0.87,64.52)	8.58 (0.92,58.89)	6.35 (1.30,55.83)	0.123
MSP-1	1.31 (0.15,2.51)	1.64 (0.20,8.18)	1.71 (0.40,9.93)	1.74 (0.71,6.14)	0.211

Table 2b. IgG1 Antibody levels across age groups in an area of unstable malaria transmission
Antigen	Median level (AU) (min, max) for age groups^b:				P value ^a (trend for age)
Antigen	2–5 yr (n=19)	6–15 yr (n=12)	16–40 yr (n=37)	>40 yr (n=28)	P value ^a (trend for age)
CSP	0.05 (0.00,4.86)*	0.00 (0.00,1.02)*	0.85 (0.02,3.29)*	0.90 (0.29,3.52)*	<0.001
LSA-1	0.53 (0.24,10.97)*	0.53 (0.03,2.40)*	0.67 (0.20,3.91)*	1.00 (0.12,15.95)*	0.055
TRAP	0.45 (0.14,2.07)*	0.26 (0.13,1.28)*	0.52 (0.00,4.40)*	1.12 (0.19,3.81)*	<0.001
AMA-1	0.18 (0.00,2.46)*	0.25 (0.00,2.32)*	0.57 (0.01,2.91)*	1.07 (0.24,4.08)	<0.001
EBA-175	0.63 (0.08,3.90)*	0.99 (0.16,18.69)*	2.76 (0.12,63.50)*	26.61 (0.44,60.07)	<0.001
MSP-1	0.83 (0.24,1.62)*	0.79 (0.16,1.69)*	1.43 (0.30,5.52)	2.31 (0.18,6.68)	<0.001

Non-parametric test for trend across ordered groups (see Materials and Methods)

Asterisk (*) indicates significantly different from antibody level for same antigen and age group in stable transmission area (P<0.05 by Wilcoxon rank-sum test).