. Author manuscript; available in PMC: 2016 Mar 1.

Published in final edited form as: Contrast Media Mol Imaging. 2014 Jun 27;10(2):135–143. doi: 10.1002/cmmi.1609

Table 3.

Histological evaluation of tissue pieces with the imaging agent-derived fluorescence exicised from the descending colon of cancer cell-implanted nude mice treated with the imaging agent.

Samples	HT-29 cells-implanted descending colon			HT-29-RFP cells-implanted descending colon
Slice position (μm)	1000	2000	3000	2000	5000	8000
Lamina muscularis mucosae	−^*	−^*	−^*	+^*	+^*	+^*
Lamina propria mucosae	+^*	+^*	+^*	+^*	+^*	+^*
Mucosal epithelia	+	+	+	−	+	+

+ invasion of implanted cancer cells; −: no invasion;

the invasion was observed in blood and/or lymph vessels