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. 2014 Nov 18;136(49):16974–16977. doi: 10.1021/ja5093437

Figure 1.

Figure 1

Dynamicity and hydrolytic degradation of HUB-containing model compounds. (a) Parameters related to the hydrolytic degradation of HUBs. (b) Structures of five HUB-containing model compounds. (c) Binding constants (Keq), dissociation rates (k–1), and water degradation kinetics of five HUB-containing model compounds shown in (b). (d) Representative NMR spectra showing the degradation of 3. The percentage of hydrolysis was determined by the integral ratio of peaks corresponding to starting compounds and hydrolysis products as shown in the inset.