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Radiosensitivity of DU 145 cells treated with PX-478. (a) DU 145 cells were treated with PX-478 under normoxia for 24 hr irradiated under normoxia and plated after 1 hr. (b) DU 145 cells were treated with PX-478 20 hr under normoxic condition for 20 hr, subjected to 1- hr hypoxia, irradiated under hypoxic condition and plated after 1 hr. Each data point represents Av ± SEM of 3 separate experiments.
