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. 2014 Dec 15;13:115. doi: 10.1186/1475-2891-13-115

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© de Moraes et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The peak effects of skin iontophoresis of acetylcholine (ACh) on cutaneous microvascular conductance (CVC, expressed in arbitrary perfusion units, APU, divided by mean arterial pressure in mmHg, upper panel); increases in CVC induced by iontophoresis of ACh (middle panel) and the area under the curve (AUC) of skin iontophoresis of ACh (lower panel) of healthy young subjects (n = 40) before (PRE) and after (POST) oral creatine supplementation. The amplitudes of ACh responses are expressed as peak CVC minus the baseline CVC. Values represent the means ± SEM.