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. Author manuscript; available in PMC: 2014 Dec 28.
Published in final edited form as: J Immunol. 2011 Jan 28;186(5):3180–3187. doi: 10.4049/jimmunol.1001252

FIGURE 4.

FIGURE 4

p120 attenuates LPS-induced PMN adhesion to pulmonary endothelial cells and PMN transendothelial migration. RLMVECs were transfected with scrambled (Sc) siRNA, p120 siRNA, empty vector, or retrovirus encoding p120 1A cDNA. Posttransfection, confluent mono-layers were formed, and then washed and stimulated with LPS (1.0 μg/ml) for the indicated times. PMN adhesion to RLMVECs and PMN transendothelial migration (TEM) were measured as described in Materials and Methods. Effects of p120 knockdown (A) and overexpression (B) on PMN adhesion to endothelial cells. Effects of p120 knockdown (C) and over-expression (D) on PMN transendothelial migration. n = 6/group. *p < 0.05 versus corresponding Sc siRNA groups.