Skip to main content
. Author manuscript; available in PMC: 2014 Dec 28.
Published in final edited form as: Horm Metab Res. 2008 Sep 25;41(1):35–39. doi: 10.1055/s-0028-1087188

Figure 3.

Figure 3

The effects of spironolactone and eplerenone on Ang II and forskolin stimulated aldosterone and cortisol production. H295R adrenal cells were stimulated with Ang II (100 nM) or forskolin (10 µM) with or without eplerenone (30 µM) or spironolactone (30 µM) for 24 h. Media concentrations of cortisol and aldosterone were measured by EIA. Values represent data from three independent experiments each ran in triplicate. SP: spironolactone, EP: eplerenone, *: p<0.05 **: p<0.01 vs. basal, ††: p<0.01 vs. Ang II, ‡‡: p<0.01 vs. forskolin.