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. Author manuscript; available in PMC: 2014 Dec 28.
Published in final edited form as: Circ Heart Fail. 2014 May 8;7(4):663–672. doi: 10.1161/CIRCHEARTFAILURE.114.001266

Figure 6.

Figure 6

Muscle A-kinase anchoring protein β (mAKAPβ) knockout inhibits transverse aortic constriction (TAC)–induced gene expression. A and B, As in Figure 4, MCM+tamoxifen (Tam) and mAKAP CKO left ventricular (LV) extracts were analyzed by immunoblot after 2- and 16-week TAC. For quantification, see Figures XIII and XIV in the Data Supplement. Control MCM+Tam and mAKAP CKO total heart RNA were assayed by Nanostring after 2-week TAC; cf Table IX in the Data Supement. C, Genes associated with pathological hypertrophy. D, Genes associated with interstitial fibrosis. *Vs sham-operated control; †vs control TAC mice. n=3 for each cohort.