Table 3.

Imaging Parameters at Baseline in the Normal, Glaucoma Suspect/Preperimetric Glaucoma, and Perimetric Glaucoma Groups of the Advanced Imaging for Glaucoma Study.

Variable	Normal	GSPPG	pa (Normal v. GSPPG)	PG	pa (Normal v. PG)
TD-OCT
Overall NFL (μm)	99.2±9.9	92.8±13.2	<0.0001	77.1±15.5	<0.0001
Superior NFL (μm)	120.2±15.2	112.1±20.5	<0.0001	92.4±23.3	<0.0001
Inferior NFL (μm)	128.4±15.8	117.8±19.7	<0.0001	91.6±25.4	<0.0001
Nasal NFL (μm)	79.1±17.2	72.6±17.1	<0.0001	64.3±16.3	<0.0001
Temp. RNFL (μm)	69.7±13.7	68.3±14.8	0.13	60.0±16.7	<0.0001
FD-OCT
Overall NFL (μm)	99.6±8.0	93.5±10.1	<0.0001	81.3±12.2	<0.0001
Superior NFL (μm)	121.0±11.0	113.8±14.7	<0.0001	97.6±18.7	<0.0001
Inferior NFL (μm)	123.6±12.1	114.6±15.0	<0.0001	94.2±19.2	<0.0001
Nasal NFL (μm)	79.6±10.8	74.2±10.4	<0.0001	67.8±11.7	<0.0001
Temp. NFL (μm)	74.3±7.9	71.7±9.7	0.0011	65.7±11.3	<0.0001
Overall GCC (μm)	97.3±6.9	92.9±8.1	<0.0001	83.5±10.8	<0.0001
Superior GCC (μm)	96.8±6.9	92.8±8.3	<0.0001	85.7±11.4	<0.0001
Inferior GCC (μm)	97.8±7.2	93.1±8.6	<0.0001	81.4±12.9	<0.0001
cSLO
Overall NFL (mm)	0.26±0.07	0.24±0.07	<0.0001	0.19±0.08	<0.0001
Rim Area (mm2)	1.41±0.40	1.32±0.34	0.0009	1.08±0.34	<0.0001
SLP
Overall NFL (μm)	53.9±4.8	52.4±7.5	0.0008	45.5±7.6	<0.0001
Superior NFL (μm)	66.6±7.4	63.9±8.8	<0.0001	55.7±11.3	<0.0001
Inferior NFL (μm)	67.01±7.2	64.9±8.6	<0.0001	55.3±12.9	<0.0001

Values are means±standard deviations; GSPPG = glaucoma suspect/preperimetric glaucoma; PG = perimetric glaucoma; TD-OCT = time-domain optical coherence tomography; FD-OCT = Fourier-domain optical coherence tomography; cSLO = confocal scanning laser ophthalmoscopy; SLP = scanning laser polarimetry; NFL = peripapillary retinal nerve fiber layer thickness; GCC = macular ganglion cell complex thickness; Temp. = temporal.

^ap-value by Generalized Estimating Equation.