Table 4.
Imaging Parameters at Baseline in the Normal, Glaucoma Suspect/Preperimetric Glaucoma, and Perimetric Glaucoma Groups of the Advanced Imaging for Glaucoma Study, Divided by Clinical Center
| UP | UM | USC | pa | |
|---|---|---|---|---|
| Normal Group | ||||
| TD-OCT NFL (μm) | 99.9±10.1 | 97.9±9.1 | 99.8±10.6 | 0.53 |
| FD-OCT NFL (μm) | 98.6±8.3 | 99.2±8.5 | 101.8±6.3 | 0.18 |
| FD-OCT GCC (μm) | 97.9±7.4 | 95.8±6.8 | 98.3±6.1 | 0.19 |
| cSLO NFL (μm) | 0.27±0.06 | 0.25±0.07 | 0.27±0.07 | 0.06 |
| cSLO Rim Area (mm2) | 1.34±0.29 | 1.32±0.42 | 1.60±0.44 | 0.0003 |
| SLP NFL (μm) | 55.2±4.8 | 51.7±4.2 | 54.6±4.5 | 0.0002 |
| GSPPG Group | ||||
| TD-OCT NFL (μm) | 94.1±13.5 | 91.1±12.4 | 92.5±13.4 | 0.25 |
| FD-OCT NFL (μm) | 94.3±9.6 | 93.3±9.6 | 92.8±11.2 | 0.77 |
| FD-OCT GCC (μm) | 93.7±8.5 | 91.4±7.2 | 93.3±8.2 | 0.044 |
| cSLO NFL (μm) | 0.24±0.07 | 0.24±0.07 | 0.22±0.08 | 0.063 |
| cSLO Rim Area (mm2) | 1.33±0.31 | 1.25±0.33 | 1.36±0.37 | 0.043 |
| SLP NFL (μm) | 53.6±5.4 | 51.1±10.8 | 51.5±5.9 | 0.038 |
| PG Group | ||||
| TD-OCT NFL (μm) | 80.9±14.3 | 73.6±16.4 | 77.1±15.2 | 0.02 |
| FD-OCT NFL (μm) | 85.3±11.1 | 79.5±13.8 | 79.9±10.6 | 0.018 |
| FD-OCT GCC (μm) | 87.0±11.4 | 80.8±10.6 | 83.6±9.7 | 0.003 |
| cSLO NFL (mm) | 0.21±0.09 | 0.18±0.07 | 0.19±0.07 | 0.078 |
| cSLO Rim Area (mm2) | 1.17±0.35 | 1.00±0.28 | 1.08±0.36 | 0.017 |
| SLP NFL (μm) | 49.0±7.1 | 41.9±6.8 | 45.1±7.5 | <0.0001 |
Values are means±standard deviations; UP = University of Pittsburgh; UM = University of Miami; USC = University of Southern California; GSPPG = glaucoma suspect/preperimetric glaucoma; PG = perimetric glaucoma; TD-OCT = time-domain optical coherence tomography; FD-OCT = Fourier-domain optical coherence tomography; cSLO = confocal scanning laser ophthalmoscopy; SLP = scanning laser polarimetry; NFL = peripapillary retinal nerve fiber layer thickness; GCC = macular ganglion cell complex thickness.
a
p-value calculated by mixed models;