Table 6.
Mixed-Effect Model Analysis of Diagnostic Group, Inter-Site, Inter-Participant, and Inter-Eye Variables for Imaging Parameters of the Advanced Imaging for Glaucoma Study.
Fixed Effects | Random Variations | ||||
---|---|---|---|---|---|
GSPPG | PG | Inter-Site | Inter-Participant | Left-Right Eye | |
TD-OCT NFL (μm) | −7.7 | −19.9 | 1.9 | 11.4 | 6.9 |
FD-OCT NFL (μm) | −6.9 | −16.5 | 1.3 | 8.9 | 5.3 |
FD-OCT GCC (μm) | −4.9 | −12.7 | 1.7 | 7.2 | 4.8 |
cSLO NFL (mm) | −0.03 | −0.06 | 0.007 | 0.05 | 0.05 |
cSLO Rim Area (mm2) | −0.12 | −0.29 | 0.064 | 0.29 | 0.19 |
SLP NFL (μm) | −2.1 | −7.4 | 1.8 | 6.1 | 4.0 |
GSPPG = glaucoma suspect/preperimetric glaucoma; PG = perimetric glaucoma; TD-OCT = time-domain optical coherence tomography; FD-OCT = Fourier-domain optical coherence tomography; cSLO = confocal scanning laser ophthalmoscopy; SLP = scanning laser polarimetry; NFL = peripapillary retinal nerve fiber layer thickness; GCC = macular ganglion cell complex thickness.