Table 2.
Baseline | During Ketamine Scan | Post Ketamine Scan | |
---|---|---|---|
CADSS (Amnesia, n = 9) | 0.0 ± 0.0 | 5.3 ± 3.9* | 0.2 ± 0.7 |
CADSS (Depersonalization, n = 9) | 0.1 ± 0.3 | 12.1 ± 7.1* | 0.8 ± 2.3 |
CADSS (Derealization, n = 9) | 1.1 ± 1.6 | 0.1 ± 0.3* | 0.9 ± 1.6 |
POMS T | 0.0 ± 0.0 | 0.3 ± 0.7 | 0.2 ± 0.6 |
POMS D | 0.6 ± 1.6 | 0.7 ± 4.3 | 0.5 ± 1.1 |
POMS A | 1.6 ± 2.4 | 4.3 ± 4.5 | 3.3 ± 4.5 |
POMS F | 3.2 ± 1.1 | 4.5 ± 5.2 | 3.9 ± 2.0 |
POMS C | 4.4 ± 2.5 | 5.2 ± 7.7 | 5.1 ± 4.7 |
POMS V | 2.2 ± 6.4 | 7.7 ± 1.5 | 4.2 ± 11.1 |
POMS Total | 3.1 ± 4.4 | 1.5 ± 0.0 | 0.9 ± 1.7 |
BDI | 0.0 ± 0.0 | 3 ± 3.5 | |
HAM-D | 0.6 ± 1.1 | 0.9 ± 1.2 | |
MADRS | 0.2 ± 0.6 | 0.0 ± 0.0 (n = 3) |
Statistics were calculated using all ten subjects, unless otherwise indicated. Baseline ratings were performed prior to the first scan, except in the case of the POMS, which was acquired before the ketamine scan. No significant differences were observed in the POMS, BDI, HAM-D, or MADRS scores at the different intervals.
Amnesia: p-value=0.035, FDR=12.5%, Depersonalization: p-value=0.009, FDR=8.6%, and Derealization :p-value=0.004, FDR=8.6%. CADSS: Clinician Administered Dissociative State Scale; POMS: Profile of Mood States; BDI: Beck Depression; HAM-D: Hamilton Rating Scale for Depression; MADRS: Montgomery–Åsberg Depression Rating Scale