Table 2.

Risk of incident AF according to the presence or absence of T2D

Models with baseline characteristics only
	No T2D at Baseline (n = 33783)	T2D at Baseline (n = 937)	P value
Number of events / person years	1023 / 528,106	56 / 13,192	...
Age-adjusted incidence rate	1.99	3.97	...
Age-adjusted model	Referent	1.95 (1.49 – 2.56)	<0.0001
Multivariable-adjusted model*†	Referent	1.87 (1.41 – 2.47)	<0.0001
+ hypertension†	Referent	1.62 (1.22 – 2.14)	0.0008
+ BMI‡	Referent	1.47 (1.11 – 1.96)	0.008
+ hypertension and BMI‡	Referent	1.37 (1.03 – 1.83)	0.03

Models using time – updated covariates
	Never T2D (n = 31053)	Baseline or incident T2D (n = 3667)	P value
Number of events / person years	955 / 507,851	124 / 33,448	...
Age-adjusted incidence rate	1.98	Baseline T2D: 3.97 Incident T2D: 3.62
Age-adjusted model	Referent	1.63 (1.35 – 1.96)	<0.0001
Multivariable-adjusted model*†	Referent	1.58 (1.30 – 1.93)	<0.0001
+ hypertension†	Referent	1.42 (1.16 – 1.73)	0.0005
+ BMI‡	Referent	1.24 (1.01 – 1.53)	0.04
+ hypertension and BMI‡	Referent	1.19 (0.97 – 1.45)	0.10
+ hypertension, BMI and intercurrent cardiovascular events‡	Referent	1.14 (0.93 – 1.40)	0.20

Data are counts, rates per 1000 person-years of follow-up, or hazard ratios (95% CIs) as appropriate. BMI = body mass index; T2D=Type 2 diabetes

^*Adjusted for age, smoking, exercise, alcohol consumption, education, race/ethnicity, hypercholesterolemia, and adult height.

^†These models were based on 1040 events in 33757 women because of missing data.

^‡These models were based on 1027 events in 33372 women because of missing data.