Table 4.

HbA1c and risk of incident AF among 24890 women with available HbA1c levels

	Hemoglobin A1c Quartiles
N=24890	1 ≤4.84%	2 4.84-5.00%	3 5.00-5.19%	4 >5.l9%	P Trend§
Number of events / participants	170 / 6275	181 / 6149	235 / 6293	249 / 6173	-
Age-adjusted incidence rate	2.05	1.99	2.33	2.37	-
Age-adjusted model	Referent	0.97 (0.79-1.20)	1.12 (0.92-1.37)	1.12 (0.91-1.37)	0.16
Multivariable-adjusted model*†	Referent	0.99 (0.80-1.22)	1.07 (0.87-1.31)	1.11 (0.90-1.36)	0.22
+ hypertension and BMI‡	Referent	0.95 (0.76-1.17)	0.97 (0.79-1.19)	0.90 (0.73-1.11)	0.35

Data are counts, rates per 1000 person-years of follow-up, or hazard ratios (95% CIs) as appropriate. BMI = body mass index

^*Adjusted for age, smoking, exercise, alcohol consumption, education, race/ethnicity, hypercholesterolemia, and adult height.

^†These models were based on 806 events in 24194 women because of missing data.

^‡These models were based on 794 events in 23921 women because of missing data.

^§P value for trend across quartiles of HbA1c using quartile-specific medians of HbA1c