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. Author manuscript; available in PMC: 2014 Dec 29.
Published in final edited form as: J Am Coll Cardiol. 2012 Sep 12;60(15):1421–1428. doi: 10.1016/j.jacc.2012.06.030

Table 4.

HbA1c and risk of incident AF among 24890 women with available HbA1c levels

Hemoglobin A1c Quartiles

N=24890 1 ≤4.84% 2 4.84-5.00% 3 5.00-5.19% 4 >5.l9% P Trend§
Number of events / participants 170 / 6275 181 / 6149 235 / 6293 249 / 6173 -

Age-adjusted incidence rate 2.05 1.99 2.33 2.37 -

Age-adjusted model Referent 0.97 (0.79-1.20) 1.12 (0.92-1.37) 1.12 (0.91-1.37) 0.16
Multivariable-adjusted model* Referent 0.99 (0.80-1.22) 1.07 (0.87-1.31) 1.11 (0.90-1.36) 0.22
    + hypertension and BMI Referent 0.95 (0.76-1.17) 0.97 (0.79-1.19) 0.90 (0.73-1.11) 0.35

Data are counts, rates per 1000 person-years of follow-up, or hazard ratios (95% CIs) as appropriate. BMI = body mass index

*

Adjusted for age, smoking, exercise, alcohol consumption, education, race/ethnicity, hypercholesterolemia, and adult height.

These models were based on 806 events in 24194 women because of missing data.

These models were based on 794 events in 23921 women because of missing data.

§

P value for trend across quartiles of HbA1c using quartile-specific medians of HbA1c