Table 2.
Distribution of Genotypes and Alleles
| SNP | Group | n | Genotypes | p | Alleles | p | OR [95% CI] | |||
|---|---|---|---|---|---|---|---|---|---|---|
| rs235913 | A/A | A/C | C/C | A | C | |||||
| PACG | 212 | 46 (21.7%) | 123 (58.0%) | 43 (20.3%) | 0.037 | 215 (0.507) | 209 (0.493) | 0.017 | 1.366 [1.055–1.776] | |
| Control | 255 | 39 (15.3%) | 141 (55.3%) | 75 (29.4%) | 219 (0.429) | 291 (0.571) | ||||
| rs183532 | A/A | A/G | G/G | A | G | |||||
| PACG | 212 | 13 (0.061) | 75 (0.354) | 124 (0.585) | 0.024 | 101 (0.238) | 323 (0.762) | 0.008 | 1.541 [1.117–2.127] | |
| Control | 255 | 6 (0.024) | 74 (0.290) | 175 (0.686) | 86 (0.169) | 424 (0.831) | ||||
| rs12076134 | G/G | G/T | T/T | G | T | |||||
| PACG | 212 | 10 (0.047) | 74 (0.349) | 128 (0.604) | 0.800 | 94 (0.222) | 330 (0.778) | 0.527 | 0.905 [0.666–1.230] | |
| Control | 255 | 15 (0.059) | 92 (0.361) | 148 (0.580) | 122 (0.239) | 388 (0.761) | ||||
| rs235875 | A/A | A/G | G/G | A | G | |||||
| PACG | 212 | 33 (0.156) | 97 (0.458) | 82 (0.387) | 0.989 | 163 (0.384) | 261 (0.616) | 0.905 | 0.984 [0.755–1.282] | |
| Control | 255 | 40 (0.157) | 118 (0.463) | 97 (0.380) | 198 (0.388) | 312 (0.612) | ||||
Bold value indicates the frequency of the AATG and AATA haplotypes was significantly higher for PACG patients than for control subjects (both p<0.001).
SNP, single-nucleotide polymorphism.