Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Improvement of wrinkles
Systematic review	55 women with wrinkles 3 RCTs in this analysis	Wrinkle score (on a 0–5 scale) with carbon dioxide laser with dermabrasion	WMD –0.10 95% CI –0.35 to +0.16		Not significant