Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
Systematic review	55 women with wrinkles 3 RCTs in this analysis	Erythema 1 month with carbon dioxide laser with dermabrasion	WMD 0.31 95% CI 0.15 to 0.47	Effect size not calculated	dermabrasion
RCT	20 women with wrinkles In review	Hypertrophic scar with carbon dioxide laser with dermabrasion
RCT	20 women with wrinkles In review	Herpetic lesions with carbon dioxide laser with dermabrasion
RCT	20 women with wrinkles In review	Proportion of people reporting worse 'post-treatment drainage' with each intervention 10/20 (50%) with carbon dioxide laser 2/20 (10%) with dermabrasion	P = 0.002	Effect size not calculated	dermabrasion