Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
RCT	20 women, aged 51–71 years, with Fitzpatrick skin type I–III and with wrinkles on upper lip In review	Erythema with carbon dioxide laser with Baker's phenol chemical peel Absolute results not reported
RCT	20 women, aged 51–71 years, with Fitzpatrick skin type I–III and with wrinkles on upper lip In review	Hypertrophic scar with carbon dioxide laser with Baker's phenol chemical peel
RCT	20 women, aged 51–71 years, with Fitzpatrick skin type I–III and with wrinkles on upper lip In review	Herpes simplex infection with carbon dioxide laser with Baker's phenol chemical peel
RCT	24 men and women, aged 43–73 years, with Fitzpatrick skin types I–III	Mean length of erythema duration 4.5 months with carbon dioxide laser 2.5 months with trichloroacetic acid chemical peel
RCT	24 men and women, aged 43–73 years, with Fitzpatrick skin types I–III	Scarring 13/24 (52%) with carbon dioxide laser 3/24 (13%) with trichloroacetic acid chemical peel
RCT	24 men and women, aged 43–73 years, with Fitzpatrick skin types I–III	Contact dermatitis to bacitracin–polymyxin B ointment with carbon dioxide laser with trichloroacetic acid chemical peel
RCT	24 men and women, aged 43–73 years, with Fitzpatrick skin types I–III	Hypopigmentation with carbon dioxide laser with trichloroacetic acid chemical peel
RCT	24 men and women, aged 43–73 years, with Fitzpatrick skin types I–III	Whitehead formation with carbon dioxide laser with trichloroacetic acid chemical peel