Skip to main content
. 2015 Jan;185(1):29–42. doi: 10.1016/j.ajpath.2014.08.026

Table 2.

Grading of 2-Year-Old Mouse Glomerulus Pathology by Histology

C57
Cfh−/−
CFH-Y:Cfh−/−
CFH-H:Cfh−/−
ID Grade ID Grade ID Grade ID Grade
1685 I 1549 IV 1501 I 1500 III
1686 II 1550 IV 1502 I 1547 IV
1687 II 1689 IV 1503 I 1548 IV
1688 I 1690 IV 1695 I 1693 III
1596 I 1694 III

The glomeruli of C57 and CFH-Y:Cfh−/− mice had similar mild histologic damage (not significant; Mann-Whitney U-test), whereas the Cfh−/− and CFH-H:Cfh−/− glomeruli were severely damaged compared with C57 (P < 0.05).