Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 1;11(1):1–10. doi: 10.7150/ijbs.10405

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

PMC Copyright notice

Bmi1 knockdown inhibits the migration and invasion ability of cancer stem-like cells (SP cells) in TSCC. (A) The expression of Bmi1, SOD2, Slug, and stem cell markers (ABCG2, Nanog) was inhibited in SP cells transfected with Bmi1 siRNA. (B, C) The migration (B) and invasion (C) abilities were significantly inhibited in Bmi1 siRNA-transfected SP cells compared to control siRNA-transfected SP cells. (D-F) The SP cells transfected with Bmi1 siRNA had significantly decreased sphere formation (D, P=0.0005), colony formation (E, P=0.0002), and proliferation (F, P=0.001) compared to control siRNA-transfected SP cells. *P < 0.05.