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. 2015 Jan 1;11(1):109–121. doi: 10.7150/ijbs.10276

Figure 6.

Figure 6

Exogenous Fas and Bax partly rescued the anti-apoptosis effect of miR-467a. At 48 h after transfection with miR-467a mimics or miR-NC mimics vector, plasmids pFas and / or pBax were transfected into EL4 cells. (A) Cell viability was measured on day 0, 2, and 4 after last transfection. FACS assay shows that exogenous Fas and Bax suppresses proliferation of miR-467a-upregulated EL4 cells. (B) At 24 h after last transfection, these cells were subjected to 7-Gy irradiation and apoptosis rate was measured 24 h later, using non-irradiated cells (0-Gy) as control. FACS assay shows exogenous Fas and Bax enhanced the apoptosis rate of miR-467a-upregulated EL4 cells. All data represent mean±SD of triple determinations.* P < 0.05.