TABLE 2.
HBV genotypes and their relationships to patients and viral featuresa
| HBV genotype | Patient feature
|
BCP and precore region mutations (no. [%])
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| No. male (%) | Mean age (yr) (SD) | No. Asian (%) | BCP
|
nt 1858
|
Precore region
|
||||
| WT | Mutant | C | T | WT | Mutant | ||||
| A | 35 (68.6) | 40.7 (11.6) | 3 (5.9) | 19 (38.0) | 31 (62.0) | 45c (90.0) | 5 (10.0) | 46 (92.0) | 4 (8.0) |
| B | 3 (100) | 49.0 (9.87) | 3 (100)† | 2 (66.7) | 1 (33.3) | 0 | 3 (100) | 2 (66.7) | 1 (33.3) |
| C | 9 (64.3) | 33.5 (16.5) | 14 (100)* | 3 (23.1) | 10b (76.9) | 0 | 13 (100) | 10 (76.9) | 3 (23.1) |
| D | 19 (76.0) | 51.1 (12.9) | 0 | 12 (48.0) | 13 (52.0) | 0 | 25 (100) | 3 (12.0) | 22 (88.0) |
| F | 10 (100) | 33.0 (7.12) | 0 | 1 (10.0) | 9 (90.0) | 7 (70.0) | 3 (30.0) | 8 (80.0) | 2 (20.0) |
| Total | 76 (73.8) | 42.0 (13.9) | 20 (19.4) | 37 (36.6) | 64 (63.4) | 52 (51.5) | 49 (48.5) | 69 (68.3) | 32 (31.7) |
a
*, P < 0.0001; †, P = 0.01. WT, wild type.
b
Includes two cases with a deletion in the BCP region.
c
Includes two cases with an adenine at nt 1858.