Table 3. Top 10 up- and top 10 down-regulated genes in ccRCC versus the normal kidney tissue.

Fold change difference and statistical significance are depicted

Top 10 up-regulated molecules	Fold change up-regulation	p-value
NDUFA4L2	53.935	<0.01
PLIN2	27.86	<0.01
NNMT	20.86	<0.01
ENO2	19.973	<0.01
AHNAK2	16.622	<0.01
NETO2	15.808	<0.01
CA9	14.483	<0.01
VWF	13.061	<0.01
COL23A1	12.752	<0.01
EHD2	12.696	<0.01
Top 10 down-regulated molecules	Fold change down-regulation	p-value
ATP6V0A4	−19.699	<0.01
CA10	−21.452	<0.01
SLC12A3	−23.667	<0.01
CLDN8	−27.113	<0.01
SERPINA5	−35.449	<0.01
KNG1	−38.45	<0.01
KCNJ1	−50.79	<0.01
RALYL	−53.576	<0.01
CALB1	−103.68	<0.01
NPHS2	−159.107	<0.01