TABLE 3.
mRNAs related to epithelial-mesenchymal transition, tissue fibrosis, and angiogenesis in human primary pterygium
| Gene symbol | Official name provided by HGNCa | Fold changeb |
|---|---|---|
| Epithelial-mesenchymal transition | ||
| CALD1 | Caldesmon 1 | 1.6 |
| CAMK2N1 | Calcium/calmodulin-dependent protein kinase II inhibitor 1 | −2.2 |
| COL3A1 | Collagen, type III, alpha 1 | 1.7 |
| FN1 | Fibronectin 1 | 2.6 |
| IGFBP4 | Insulin-like growth factor binding protein 4 | 1.5 |
| MMP2 | Matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 1.8 |
| MSN | Moesin | 1.5 |
| NOTCH 1 | Notch 1 | 1.5 |
| PDGFRB | Platelet-derived growth factor receptor, beta polypeptide | 1.6 |
| SPARC | Secreted protein, acidic, cysteine-rich (osteonectin) | 1.6 |
| TGFB2 | Transforming growth factor, beta 2 | 1.6 |
| TFPI2 | Tissue factor pathway inhibitor 2 | −2.3 |
| VIM | Vimentin | 1.5 |
| Tissue fibrosis | ||
| ACTA2 | Actin, alpha 2, smooth muscle, aorta | 2.7 |
| AQP1 | Aquaporin 1 (Colton blood group) | 2.7 |
| CCL19 | Chemokine (C-C motif) ligand 19 | 2.0 |
| COL3A1 | Collagen, type III, alpha 1 | 1.7 |
| CTGF | Connective tissue growth factor | 2.0 |