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. 2015 Jan;185(1):43–54. doi: 10.1016/j.ajpath.2014.09.007

Figure 2.

Figure 2

Disruption of TRPV1 gene attenuates chronic binge ethanol (EtOH)–induced liver injury. A: Plasma ALT levels. B: Plasma AST levels. There is a significant increase in ALT and AST levels in response to ethanol in WT, but not TRPV1−/−, animals. C: Representative image of hepatic hematoxylin and eosin (H&E) staining. D: Representative image of Oil-Red-O staining. E: Liver TG levels. F: Liver cholesterol levels. A, B, E, and F: Values are means ± SEM. n = 5 to 9 animals per group (A, B, E, and F). ∗P < 0.05 (two-way analysis of variance, followed by the Tukey's multiple-comparison test). Original magnification: ×200 (C); ×400 (D).