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. 2015 Jan;185(1):43–54. doi: 10.1016/j.ajpath.2014.09.007

Figure 6.

Figure 6

TRPV1−/− mice exhibit significantly decreased hepatic PAI-1 expression and fibrin deposition. A: Hepatic PAI-1 mRNA. PAI-1 levels were measured by RT-qPCR, and normalized to 18s rRNA as an internal control. B: Representative confocal images depict immunofluorescence detection of hepatic fibrin (green) against a Hoechst counterstain (blue). A: Values are means ± SEM. n = 5 to 6 animals per group (A). P < 0.05 (two-way analysis of variance, followed by the Tukey’s multiple-comparison test). Original magnification, ×400 (B). EtOH, ethanol.