Table 4.

Correlations between PEDF Expression and Clinicopathological Characteristics of Melanoma Patients (n = 41)

Characteristic	Value	P value, H:0 τ = 0	Kendall’s τB∗
Age (years)		0.6546	−0.05642
Mean	54
Median	54
Range	21–84
Sex		0.34†
Male	26
Female	15
Anatomic location (no.)		0.1471†
Head & neck	7
Upper extremities	9
Trunk	17
Lower extremities	8
Histological subtype (no.)		0.8008†
Superficial spreading	33
Nodular	6
Lentigo maligna	1
Other	1
Tumor thickness (mm)		0.1413	−0.18608
Mean	2.67
Median	1.41
Ulceration (no.)		0.1252	0.23179
Present	9
Absent	32
Mitotic index (/mm2)		0.053	0.25852
Mean	4.9
Median	3
Clark’s level		0.6077	−0.07342
II	3
III	11
IV	23
V	4
Regression	40	0.7638	0.04597
Present	7
Absent	33
Clinical follow-up (months)		0.1076	0.20138
Mean	47.6
Median	34.5
Range	3.9–120.7
AJCC stage		0.0796	0.24762
I	7
II	12
III	3
IV	19
Nodal metastasis		0.0868	0.25889
Positive	21
Negative	20
Organ metastasis		0.3225	0.14956
Positive	12
Negative	29
Distant metastasis		0.0331	0.32215
Positive	19
Negative	22
Death of disease		0.1273	0.23055
Positive	14
Negative	27
Angiogenic parameters	32
Blood vascular density (/mm2)		0.0675	0.25894
Mean	52.6
Median	47
Blood vessel size (mm2)		0.3653	−0.12821
Mean	662.7
Median	634.82
Blood vascular area (%)		0.3031	0.14596
Mean	3.3
Median	3.2

P values in bold are statistically significant (<0.05).

^∗Positive values of τ_B denote a positive correlation; negative values, an inverse correlation.

^†Mantel–Haenszel χ² test.