Table 2.

Association of kidney stone disease with all-cause and cardiovascular mortality

		Men		Women		Combined
Regression Model		HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
All-cause mortality	Unadjusted	2.03 (1.62–2.53)	<0.0001	1.81 (1.35–2.42)	<0.0001	1.95 (1.64–2.33)	<0.0001
	Model 1	1.03 (0.85–1.25)	0.8	1.21 (0.95–1.55)	0.1	1.08 (0.93–1.26)	0.3
	Model 2	0.99 (0.81–1.20)	0.9	1.05 (0.82–1.34)	0.7	1.00 (0.85–1.17)	1.0
	Model 3	0.96 (0.79–1.18)	0.7	1.03 (0.80–1.31)	1.0	0.99 (0.85–1.16)	0.9
Cardiovascular mortality	Unadjusted	2.05 (1.60–2.62)	<0.0001	2.06 (1.40–3.04)	0.0002	2.05 (1.60–2.62)	<0.0001
	Model 1	0.96 (0.70–1.32)	0.8	1.34 (0.94–1.90)	0.1	1.07 (0.84–1.36)	0.6
	Model 2	0.88 (0.64–1.22)	0.5	1.09 (0.79–1.51)	0.6	0.94 (0.74–1.19)	0.6
	Model 3	0.88 (0.64–1.21)	0.4	1.08 (0.78–1.48)	0.7	0.94 (0.75–1.19)	0.6

Variables adjusted for: Model 1=age, gender, race, and poverty income ratio. Model 2=body mass index, total cholesterol, high density lipoprotein, physical activity, histories of hypertension, diabetes and cardiovascular disease, in addition to model 1. Model 3: serum C-reactive protein, serum 25-hydroxyvitamin D, and estimated glomerular filtration rate, in addition to model 2