. 2014 Dec 23;5(6):e01824-14. doi: 10.1128/mBio.01824-14

TABLE 1 .

Frequency of isolates by year and diversity/divergence estimates

Yr	Frequency according to:		Total^b	Diversity^c	Divergence^d	Within-group hqSNP difference^e
Yr	UF-EPI^a	Katz et al. (9)	Total^b	Diversity^c	Divergence^d	Within-group hqSNP difference^e
2010	9	13	22	0.011 (0.004)		0.636 (0.219)
2011		14	14	0.098 (0.016)	0.056 (0.008)	5.868 (0.855)
2012	23	1	24	0.073 (0.018)	0.058 (0.018)	3.978 (0.866)
Total	32	28	60

^{^a}

The isolates listed were sampled by the University of Florida Emerging Pathogen Institute (UF-EPI).

^{^b}

Four non-O1/O139 isolates are not listed and were not included in the diversity/divergence estimates.

^{^c}

Diversity estimates of the mean evolutionary diversity within year-specific subpopulations. The number of nucleotide substitutions per hqSNP site from mean diversity calculations within subpopulations is shown with the standard error obtained by bootstrap estimates (1,000 replicates) in parentheses.

^{^d}

Divergence estimates and standard errors (in parentheses) of average evolutionary divergence compared to sequence sampled during the first epidemic outbreak in 2010. The number of nucleotide substitutions per hqSNP site from averaging over all sequence pairs within groups is shown.

^{^e}

Mean within-group hqSNP differences and standard errors (in parentheses) by collection year.