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. Author manuscript; available in PMC: 2014 Dec 29.
Published in final edited form as: Cancer. 2014 Feb 7;120(9):1319–1328. doi: 10.1002/cncr.28550

Table 2.

Univariate analysis for overall survival and distant progression-free survival

No. of
patients*
5-year OS
(%)
p Value 5-year DPFS
(%)
p Value
Race
White 119 30 0.05 20 <.001
Black 32 17 0
Other 21 38 27
ECOG Performance Status
0-1 126 31 0.01 18 0.002
>1 29 11 5
Menopausal status
Post 100 34 0.44 21 0.79
Pre 69 27 14
Hormone receptor
Pos 89 31 0.12 15 0.81
Neg 77 25 18
HER2 receptor
Pos 45 44 0.002 25 <.001
Neg 117 20 11
Grade
1 3 67 0.73 33 0.47
2 38 24 15
3 120 28 17
LVSI
Yes 78 27 <.001 16 <.001
No 39 52 40
Unknown 55
Histology
Ductal 136 30 0.92 18 0.88
Lobular 13 42 19
Mixed 14 19 9
Systemic therapy
Chemo only 117 28 0.63 17 0.42
Chemo+endocrine 55 29 8
Response to systemic therapy
Non-responders 69 13 <.0001 8 <.0001
Responders 98 41 24
Locoregional therapy
None 75 9 <.0001 0 <.0001
Radiotherapy alone 18 14 15
Surgery alone 11 25 18
Surgery+radiotherapy 68 50 32
Surgery
Yes 79 47 <.0001 30 <.0001
No 93 10 3
Surgical intent
Curative 47 49 0.66 35 0.56
Local control 32 44 24
Margin status
Negative 60 48 0.92 33 0.38
Positive 7 47 42
Close 8 40 25
pCR
Yes 12 60 <.001 61 <.001
No 67 26 13
# distant disease sites
1 94 34 0.05 24 <.001
>1 78 18 6
*

Patients with unknown data were excluded, thus totals may vary

Abbreviations: OS, overall survival; DPFS, distant progression-free survival; ECOG, Eastern Cooperative Oncology Group; LVSI, lymphovascular space invasion; pCR pathologic complete response