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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Bioessays. 2013 Nov 18;36(1):107–117. doi: 10.1002/bies.201300090

Table 1.

Methods for detecting DNA methylation and its oxidation

Affinity purification Base-resolution
5mC DNA Immunoprecipitation (DIP/MeDIP)[72], MBD-Seq[75–76], TET-assisted methyl-cytoisne selective labeleing (biotin, TAmC-Seq)[74] Bisulfite sequencing [80], Single-molecule Real-Time Sequencing (SMRT) [76], Oxidative Bisulfite Sequencing (OxBS-Seq)[79]
5hmC DIP (5hmC-DIP)[64,73,78], JBP1[68], 5hmC selective labeling (biotin, 5hmC-Seal) [71]
Glucosylation/Periodate oxidation/Biotinylation (GLIB) [66]		 TET Assisted Bisulfite Sequencing (TAB-Seq)[25], SMRT[77]
5fC DIP (5fC-DIP)[70], 5fC-Seal (biotin)[62] 5fC Chemical Assisted Bisulfite Sequencing (fCAB-Seq)[70]
5caC DIP (caC-DIP)[70] 5caC Chemical Assisted Bisulfite Sequencing [65]